Antisense and RNAi Therapeutics Market Set for Rapid Growth, to reach Value around US$ 3.06 Bn. by 2029

Prakashtorase
4 min readDec 22, 2023

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Antisense and RNAi Therapeutics Market

Zion Market Research has published a new report titled “Antisense and RNAi Therapeutics Market by Technology (RNAi [miRNA, and siRNA], and Antisense RNA), by Route of Administration (Pulmonary, Intravenous, Intra-Dermal, Intra-Peritoneal, Topical, and Others), and by Indication (Oncology, Cardiovascular Diseases, Renal Diseases, Neurodegenerative Diseases, Respiratory Diseases, Genetic Diseases, Infectious Diseases, and Other Disease Indications): Global Industry Perspective, Comprehensive Analysis and Forecast.

According to the report, global demand for Antisense and RNAi Therapeutics Market was valued at US$ 1.47 Bn. in 2022 and is expected to reach US$ 3.06 Bn. by 2029, at a CAGR of 11% during the forecast period of 2022 to 2029.

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Antisense is a technology that includes the synthesis of nucleic acid strands which bind to the splicing site or mRNA on the pre-mRNA and inactivates it efficiently. It is a very predominant technology used by researchers, and pharma-biotech companies for numerous applications like research, diagnostics, and therapeutics. RNAi therapeutics has vast scope in the treatment of cancer and neurodegenerative disorders. For treatment of rare and serious chronic diseases RNAi and antisense therapeutics are novel therapeutic options.

The market for antisense and RNAi therapeutics is mainly driven by the increasing cancer cases worldwide. Moreover, collaborations between pharma and biotech companies, technological advancements are also increasing. Besides, quick commercialization of pipeline therapeutics is also providing competitive edge to the market with multifactorial disease targeting which is likely to open new avenues for antisense and RNAi therapeutic market. However, high expenditure on research, threat of failure, and hurdles in drug delivery systems are the some of the factors restraining market growth.

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The market for antisense and RNAi therapeutics is segmented based on indication, technology, route of administration, and regions. The market is segmented on the basis of technology into antisense RNA, and RNAi. The RNAi technology is further segmented into siRNA, and miRNA. The segment for antisense RNA held major share of the market due to its potential usage in therapeutics. Moreover, these molecules are also tested for the prevention of diseases onset and also to halt disease progression. On the basis of route of administration the market is segmented into topical, intra-peritoneal, intra-dermal, pulmonary, intravenous, and other delivery methods. Scientists in this field are developing new delivery systems like nanocarriers, in order to promote in-vivo delivery of oligonucleotides.

On the basis of indication the market for antisense and RNAi therapeutics is segmented into neurodegenerative diseases, respiratory diseases, cardiovascular diseases, genetic diseases, oncology, renal diseases, infectious diseases, and other disease indications. The segment for oncology held major share of the market owing to large number of research grants and licensing revenue which are associated with cancer-based trials for RNAi and antisense therapeutics.

Regional segmentation includes the current and forecast demand for Asia Pacific, North America, Latin America, Europe, and Middle East & Africa with its further bifurcation into major countries. North America held major share of the market in 2018, owing to increasing number of clinical trials that is supporting the process of initiation for developing antisense therapeutics and huge number of government policies supporting them in this region.

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Some of the key players in antisense and RNAi therapeutic market -

  • miRagen Therapeutics
  • Isis Pharmaceuticals
  • Santaris
  • Antisense Therapeutics
  • Alnylam Pharmaceuticals
  • Silence Therapeutics.

This report segments the global antisense and RNAi therapeutics market as follows:

Global Antisense and RNAi Therapeutics Market: Technology Segment Analysis

  • RNAimiRNAsiRNA
  • Antisense RNA

Global Antisense and RNAi Therapeutics Market: Route of Administration Segment Analysis

  • Pulmonary
  • Intravenous
  • Intra-dermal
  • Intra-peritoneal
  • Topical
  • Other

Global Antisense and RNAi Therapeutics Market: Indication Segment Analysis

  • Oncology
  • Cardiovascular Diseases
  • Renal Diseases
  • Neurodegenerative Diseases
  • Respiratory Diseases
  • Genetic Diseases
  • Infectious Diseases
  • Other Disease Indications

Global Antisense and RNAi Therapeutics Market: Region Segment Analysis

  • North AmericaU.S.
  • EuropeUKFranceGermany
  • Asia PacificChinaJapanIndia
  • Latin AmericaBrazil
  • Middle East and Africa

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